CytoCell Prenatal 13, 18 and 21 Enumeration FISH Probe

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Product summary

Technology FISH
Application Cytogenetics & rare disease
Areas of interest Constitutional
Region 13q14.2
18p11.1-q11.1
21q22.13
Label
Product Code LPA 005 (10 tests)
LPA 005-S (5 tests)
Regulatory Status In vitro diagnostic. This product is intended to be used on amniocytes.

Documentation

Chromomaps

13q14.2

21q22.13

18p11.1-q11.1

Overview

Summary

The Prenatal Enumeration range allows detection of trisomies 13, 18 and 21 (Patau, Edwards and Down syndromes) and sex chromosome aneuploidies utilising an overnight hybridisation protocol.

CytoCell^® Prenatal kits provide the benefits of:

Overnight hybridisation protocol demonstrating high intensity signals and minimal background
Economical kit formats: 5, 10, 30* or 50* tests
Liquid stable reagents premixed in hybridisation solution and provided with DAPI counterstain

Probe information

13 unique sequence (13q14.2) Green
18 centromere 18p11.1-q11.1 (D18Z1) Blue
21 unique sequence (21q22.13) Orange

*Not available for LPA002, 003, 004 or 005

Fluorescence in situ hybridisation (FISH) microscope image of the CytoCell Prenatal 13, 18 and 21 probe.

What our customers say

Running our PETS protocol was taking upwards of 5 hours to complete based on the previous SOP. After the technical training visit from CytoCell, we were able to make some tweaks to reduce the protocol time down to just 1 hour and 15 minutes, with the same or better results.