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CytoCell fluorescence in situ hybridisation (FISH) logo.

Product summary

  • Technology FISH
  • Application Cytogenetics & rare disease
  • Areas of interest Constitutional
  • Region 13q14.2
    18p11.1-q11.1 (D18Z1)
    21q22.13
    Xp11.1-q11.1 (DXZ1)
    Yp11.1-q11.1 (DYZ3)
  • Label      
  • Product Code LPA 001-50 (50 tests)
    LPA 001-30 (30 tests)
    LPA 001 (10 tests)
    LPA 001-S (5 tests)
  • Regulatory Status In vitro diagnostic. This product is intended to be used on amniocytes.

Documentation

Ancillary products

Chromomaps

13q14.2

Fluorescence in situ hybridisation (FISH) chromosome map showing a probe targeting the region 13q14.2. Expand image.

21q22.13

Fluorescence in situ hybridisation (FISH) chromosome map showing a probe targeting the region 21q22.13. Expand image.

Xp11.1-q11.1 (DXZ1)

Fluorescence in situ hybridisation (FISH) chromosome map showing a probe targeting the region Xp11.1-q11.1 (DXZ1). Expand image.

Yp11.1-q11.1 (DYZ3)

Fluorescence in situ hybridisation (FISH) chromosome map showing a probe targeting the region Yp11.1-q11.1 (DYZ3). Expand image.

18p11.1-q11.1 (D18Z1)

Fluorescence in situ hybridisation (FISH) chromosome map showing a probe targeting the region 18p11.1-q11.1 (D18Z1). Expand image.

Overview

Summary

The Prenatal Enumeration range allows detection of trisomies 13, 18 and 21 (Patau, Edwards and Down syndromes) and sex chromosome aneuploidies utilising an overnight hybridisation protocol.

CytoCell Prenatal kits provide the benefits of:

  • Overnight hybridisation protocol demonstrating high intensity signals and minimal background
  • Economical kit formats: 5, 10, 30* or 50* tests
  • Liquid stable reagents premixed in hybridisation solution and provided with DAPI counterstain

 

Probe information

Each kit contains the following probe sets:

Probe set 1

  • X centromere Xp11.1-q11.1 (DXZ1) Green
  • Y centromere Yp11.1-q11.1 (DYZ3) Orange
  • 18 centromere 18p11.1-q11.1 (D18Z1) Blue

Probe set 2

  • 13 unique sequence (13q14.2) Green
  • 21 unique sequence (21q22.13) Orange

*Not available for LPA002, 003, 004 or 005

Fluorescence in situ hybridisation (FISH) microscope image of the CytoCell Prenatal X, Y, 13, 18 and 21 probe.

Expand image.
Fluorescence in situ hybridisation (FISH) microscope image of the CytoCell Prenatal X, Y, 13, 18 and 21 probe.

Expand image.
Fluorescence in situ hybridisation (FISH) microscope image of the CytoCell Prenatal X, Y, 13, 18 and 21 probe.

Expand image.

What our customers say

I first came across CytoCell FISH probes in a previous lab I worked in and I was struck by the quality of the products. Since this time, I have been recommending and introducing CytoCell probes across all application areas — now they are the primary FISH probes used in our lab. They have an excellent range of products and their ready-to-use reagent format saves considerable time.

Elizabeth Benner, Medical Technologist, University of Arizona Health Network, USA.

Elizabeth Benner

Medical Technologist, University of Arizona Health Network, USA

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