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Developed in partnership with myeloid cancer experts to the latest WHO guidance, the panel can identify novel fusion partners — providing more comprehensive and informative analyses than possible using PCR-driven methods. The figure (right) shows the consistent and confident detection of MECOM overexpression in [A] serial dilutions of HNT-34 cell line as well as [B] research and commercial samples, including positive and negative controls.

The CDKN2A Probe covers CDKN2A (P16) gene and flanking regions, and is labeled in gold. The Centromere 17 Probe covers the chromosome 17 centromere (D17Z1) region and is labeled in aqua. The Centromere 3 Probe covers the chromosome 3 centromere (D3Z1) region and is labeled in red. The Centromere 7 Probe covers the chromosome 7 centromere (D7Z1) region and is labeled in green.

Familial Hypercholesterolaemia (FH) is a genetic condition which results in a high cholesterol level and subsequently leads to a higher risk of early heart disease. OGT is offering an optimised NGS panel which has selected the most relevant genes and SNPs implicated in FH, for your research needs. The figure (left) shows a double deletion on the LDLR gene, as visualised by Interpret software.