Gain an understanding of the relationship between sequencing depth and Variant Allele Frequency (VAF) sensitivity, which plays a significant role in accurately detecting genetic variants, especially in Measurable Residual Disease (MRD) detection.
Read articleGain an understanding of the relationship between sequencing depth and Variant Allele Frequency (VAF) sensitivity, which plays a significant role in accurately detecting genetic variants, especially in Measurable Residual Disease (MRD) detection.
ReadLearn how to combat high background fluorescence in your FISH assays with inside tips on sample preparation, hybridisation conditions and more.
ReadAt OGT we are proud of the collaborations we have with labs all over the world. In this blog discover how Norah O. Akinola, Professor of Haematology at the Obafemi Awolowo University in Nigeria, worked with OGT experts to establish a FISH laboratory by upgrading their existing cytogenetics facility.
ReadWe explore the guidelines and the different methods for fusion event detection, including the potential of RNA-based NGS to help pave the way for personalised therapies and improved patient outcomes.
ReadIf you currently rely upon IVDD probes and are unsure about when or how to switch to a new IVDR platform, we’re here to help you. Find out why you should move to IVDR...
ReadToday we celebrate International Day of Women and Girls in Science. Our OGT family includes many women having successful STEM careers. Take a look at some of their stories across various roles in the OGT organisation...
ReadIn the second part of our latest blog series - “Old biomarkers, new tricks" - we highlight the ongoing efforts to bring BCL-2 inhibitors to the forefront in t(11:14) translocation cases of multiple myeloma, and how FISH probes can support clinical investigations.
ReadDidn’t get a chance to talk to us at ASH 2023? Read the first part of our latest blog series, which describes the potential of menin inhibitors for acute leukaemia, including the use of IVDR approved FISH probes in clinical trials.
ReadIn March 2023, we became the very first manufacturer of FISH probes to be granted IVDR certification. In our latest blog we speak with Steve Chatters, Executive Vice President of Regulatory, Medical and Quality Affairs, about OGT's long-standing expertise in healthcare regulation, and the journey towards IVDR certification.
ReadWe sit down with two of our Field Application Scientists, Ashley Hart and Jenny Morse, to discuss the technical expertise they offer to OGT customers all over North America. And we chat with one of our customers, Kathleen Kretkowski, about a real-life example of OGT support in action.
ReadMyeloid malignancies are a group of diseases with wide heterogeneity. In this blog, we will explore the KMT2A gene, previously known as the MLL gene, and its influence upon myeloid malignancies.
ReadIs NGS set to become the new gold standard in constitutional genetics? Discover how NGS offers greater insight into indels, CNVs, LOH, mosaicism and more.
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