CytoCell Angelman (UBE3A/D15S10) Region FISH Probe

Product summary

Technology FISH
Application Cytogenetics & rare disease
Areas of interest Constitutional
Region 15q11.2-q12
15q26.3
Label
Product Code LPU 006-A (100μl)
LPU 006-SA (50μl)
Regulatory Status Analyte specific reagent. Analytical and performance characteristics are not established.

Documentation

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Chromomaps

15q11.2-q12 (UBE3A) / 15q26.3 (15qter)

FISH chromosome map showing a probe targeting a region associated with Angelman syndrome (UBE3A gene).

Overview

Probe specification

UBE3A, 15q11.2-q12, Red
15qter, 15q26.3, Green

The Angelman (UBE3A/D15S10) probe is 108kb, labeled in red, covers most of the UBE3A gene and includes the D15S10 marker. The 15qter subtelomere specific probe (clone 154P1), labeled in green, allows identification of chromosome 15 and acts as a control probe.

Fluorescence in situ hybridization (FISH) microscope image of the CytoCell Angelman (UBE3A/D15S10) Region probe.

What our customers say

The quality of the products we have received from CytoCell have been excellent. The FISH probes they provide to us give intense, strong signals and are a pleasure to count. What has really stood out however has been the level of support and assistance provided by CytoCell’s application specialists. The team worked very closely alongside our own during the adoption of this product and spent many hours with us perfecting the technique, going above and beyond what I would expect during the transition period. Source BioScience absolutely demand high quality products and service to be able to deliver our results with confidence, and that is what we have received from CytoCell.

Neil Ryan

Laboratory Operations Manager, Source BioScience, UK