CytoCell IGH/CCND1 Translocation FISH Probe (Solid Tumor)

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Product summary

Technology FISH
Application Solid tumor
Region 11q13.3
14q32.33
Label
Product Code LPS 031-A (100μl)
Regulatory Status Analyte specific reagent. Analytical and performance characteristics are not established.

Documentation

Ancillary products

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Chromomaps

14q32.3 (IGH)

Fluorescence in situ hybridization (FISH) chromosome map showing a probe mix targeting the IGH gene.

11q13.3 (CCND1)

Fluorescence in situ hybridization (FISH) chromosome map showing a probe mix targeting the CCND1 gene.

Overview

Probe specification

IGH, 14q32.3, Green
CCND1 (BCL1), 11q13.3, Red

The IGH/CCND1 product consists of probes, labeled in green, covering the Constant, J, D and Variable segments of the IGH gene, and CCND1 probes labeled in red. The CCND1 probe mix contains a 267kb probe centromeric to CCND1 gene, covering the region between the D11S1100 and the D11S4095 markers, and a second 223kb probe covering the telomeric end of CCND1 gene.

Fluorescence in situ hybridization (FISH) microscope image of the CytoCell IGH/CCND1 Translocation, Dual Fusion probe.

What our customers say

It was very important for us to have more consistent results with our probes — easy-to-read bright signals and a range of vial sizes, which is much more cost-effective. It also was critical to upgrade our pretreatment kit to expedite the analysis of FFPE samples. We can now complete the process in about 90 minutes.